The first prize – the elderly Over 60 years old, older people, the legs themselves are not good, and the joints are not good. And gout likes to bully such elderly people. Long years of wear and tear on the joints, calcium loss, little cartilage tissue left. “Where the evil comes together, its qi will be deficient”, and there are also uric acid crystals hidden in the cracks of the tissue. A careless, uric acid crystals come out to brush up their presence and beg for attention. So the chances of the elderly suffering from gout are not generally high. The data shows that the ratio of men to women with gout is about 20:1. Men are more likely to suffer from gout than women because of androgens, which are particularly fond of uric acid and inhibit the kidneys from excreting uric acid, leading to higher levels of uric acid in the body and accelerating the formation and deposition of uric acid crystals. The formation and deposition of uric acid crystals is accelerated. Menopausal women also face a decline in estrogen and a rise in androgens, leading to an increase in uric acid levels. The scout – patients with a family history of gout According to big data, 3.5-25% of gout patients have a family history of gout, which means that gout can be influenced by genetic inheritance. As with diabetes, in addition to the genes inherited from our parents, they also develop our lifestyle and eating habits, which can affect the expression of our genes and cause the disease, and this change is also inherited, which is epigenetics. The fourth place – people who have been athletes The original athletes, a large amount of exercise, the last issue we talked about a large number of sports will lead to a large number of ATP burning, purines are constantly released into the blood, thus a constant flow of uric acid formation, plus if the original sports when the joints have been injured, more will lead to the deposition of uric acid in them, triggering the onset of gout. In addition to the above four cases, the rest of the gout, are their own eat out. 1, love to eat meat: pork, beef, lamb, purine content are very high, and seafood is synonymous with high purine 2, love to drink: especially beer, purine content is like Shijiazhuang’s air index, high to burst. What about the purines eaten? As mentioned in the last issue, the purines that enter the bloodstream will be metabolized by the liver to generate a steady stream of uric acid, which finally becomes a steel needle stuck in the joints.