It is well known that women go through menopause as they age. Menopause is a necessary stage when women move from adulthood to old age, and is the age when women transition from a state of vigorous reproductive function to a post-reproductive phase. An important sign of menopause in women is menopause, so the endocrine, physiological and clinical changes that occur during menopause are also called perimenopausal syndrome. So for men, is there a male menopause as well? Does male menopause syndrome also exist? In fact, menopause is not unique to women. Aging is a common feature of all life phenomena in nature, and both men and women will experience a transition from their reproductive years to their post-reproductive years as they grow older. However, male menopausal syndrome differs from female menopausal syndrome due to physiological differences between men and women, especially the pattern of sex hormone decline in both sexes. Although partial androgen deficiency is an important cause of male menopausal syndrome, sex hormone decline is not the only cause of male menopausal symptoms, which may also include problems with androgen receptors and many other causes. What we mean by male menopause syndrome is not a single disease, but a group of diseases. It is a group of clinical, biochemical, and physiological syndromes associated with aging, with or without a decrease in serum testosterone levels. This is the one that occurs because of androgenic problems we call late-onset hypogonadism, and it is the one that we have studied the most and recognized so far. However, it is not entirely different from male menopausal syndrome in the narrower sense. The main symptoms of male menopause syndrome include: 1. decreased sexual desire and erectile function, especially spontaneous erections at night and morning erections, loss of interest in sex, decreased erectile hardness, unsuccessful intercourse, etc.; 2. mood changes with decreased mental and spatial orientation, poor concentration, insomnia, forgetfulness, easy fatigue, irritability and depression, nervousness and fear, etc.; 3. muscle reduction with decreased muscle strength 4, hair thinning, slow growth of beard, skin atrophy changes, etc.; 5, decreased bone mineral content, can cause osteoporosis, bone and joint pain, etc.; 6, visceral fat deposits, fatty liver, etc. Not all of the above symptoms may appear, which may be more obvious with one or more symptoms, with or without reduced serum testosterone levels. In order to facilitate patients’ recognition and early detection, it is clinically recommended that patients use the ASM scale or ADAM questionnaire for self-assessment (see the attached table) and seek early medical attention if they have any problems. The use of androgens has clear clinical indications and contraindications, and must be treated scientifically under the guidance of a doctor.