A. About the toxicity of the epiphyllum Epiphyllum is toxic, so the key to ensure the safe and effective use of epiphyllum is to prescribe the right medicine. The patient’s face is dark or slightly swollen, eyes are dull, speech is weak, and he is sleepy, which is described in the “Treatise on Typhoid Fever” as “a weak pulse, but he wants to sleep”. The pulse of “appendage” is an important indication for the application of appendage. However, there are sometimes clinical changes, such as when the pain is severe, the pulse can appear floating or flooding, but heavy pressure is lack of bottom force, and, after the pain stops, the pulse will return to its original state of sinking. The decoction method of Radix et Rhizoma is very delicate. If it is used for anti-shock, it should be decocted for a long time to increase the effectiveness and detoxification. Generally, for 10 grams, it should be decocted for 20 minutes; for 20 grams, it should be decocted for 40 minutes; for 30 grams, it should be decocted for 60 minutes; that is, for every 10 grams, the decoction time should be increased by 20 minutes. However, when used for pain relief, the decoction time should not be too long. Some people propose a new usage of Radix et Rhizoma, which is to pound it into a coarse powder and decoct it in boiling water for 10 minutes, and then taste it without numbness. It is the experience of Zhu Liangchun, a veteran herbalist, that the water used for decocting Radix Aconiti must be put in at one time and not added in the middle. In addition, Wu Peiheng, the “God of Fire” in Yunnan, also advocates using a large pot of water to decoct the herbs for a long time. Chen Susheng introduced the experience of his teacher, Mr. Zhu Weiju, who firstly paid attention to the specifications of the concoction of Radix Aconiti, and believed that it is better to cut and break the various concoctions of Radix Aconiti; secondly, he paid attention to the antidotes of the supervised Radix Aconiti (such as dry ginger, licorice, magnet); finally, he paid attention to the conditions of decoction, which advocated using open first dip and then decoction, requiring wide water (increase the amount of water), slow fire penetration (no rapid fire heating), and decoction time of more than 2-3 hours, and then adding The decoction time is scaled according to the dosage. For patients who have never taken Radix Aconiti before, it is advisable to gradually increase the dosage in small amounts (plus antidote) until it reaches the strength of the effect. In addition to the disease state of the patient, it is also related to the dosage, decoction time, season and other factors. Therefore, it is difficult to unify the dosage of Radix Aconiti, and there is a great difference in the amount. Some advocate a dosage of 3-9 grams, while others advocate a dosage of 30 grams or more. It has been reported that in the treatment of a cold and damp painful paralysis with Wu Tou Tang, the Radix Aconiti was added from 31 grams to 62 grams in 3 doses. The patient mistakenly took another 186 grams of Radix Aconiti as a decoction, and was unharmed after taking it. The next day, the pain in the joints was lost, and the blue and cold feeling in the inner thighs was lost. However, the clinical use of the herb, it is still appropriate to start with a small dose, and then gradually increase the dosage according to the patient’s response and the needs of the disease. Zhang Zhongjing use of the seeds of the two dose sections, the large dose of 3-5, mostly for the treatment of joint pain or heart and abdominal pain; small dose of 1-2, mostly for the treatment of pulse sinking micro, extremities syncope cold, etc.. Personally, I think: small doses (below 6 grams) are used for Yang deficiency and Qi deficiency patients with short duration of illness and fair constitution, which can play the role of warming Yang and transforming Qi. Large doses (10 grams or more) can be used for patients with long duration of illness, Yang Qi deficiency, leakage of sweat, spontaneous sweating and weakness of long-standing illness into the ligament, pain, can play a role in warming Yang, stopping sweating and analgesia. Five, on the use of the herb with the use of the herb must be used with licorice, ginger. Tao Hongjing mentioned in “The Collected Notes on the Materia Medica” that “the common use of Radix et Rhizoma must be accompanied by licorice, ginseng, and ginger, which are also used to control its toxicity”. Generally, the toxicity of Si Wei Tang is greatly reduced when using 9-12 grams of Radix Aconiti, 6-9 grams of ginger and 12 grams of roasted licorice. The symptoms of poisoning with Radix et Rhizoma Polygonati and Chuan Wu are mainly neurological and circulatory, followed by digestive system symptoms. The symptoms of poisoning are nausea, vomiting, abdominal pain, diarrhea, dizziness, numbness of the limbs and body, coldness, followed by dilated pupils, blurred vision, difficulty in breathing, hand and foot convulsions, decreased blood pressure and body temperature. Aconitine can directly poison cardiac muscle cells, so its cardiotoxicity is the most lethal, and it is very likely to cause atrial fibrillation when poisoned. In ancient times, it was relieved by decoction of licorice, Huanglian, cinnamon, mung bean and black bean. In modern times, atropine, procaine, etc. are injected and the stomach is lavaged with 1-2 ellagic acid, and emetic, activated charcoal, and heat preservation and oxygen are given as appropriate. Oral administration of strong tea also has an antidote, the purpose is to precipitate the generation of alkali.