Depression is one of the common psychiatric disorders, with more female than male patients developing it. The manifestations of depression are more varied, with persistent and pronounced depression as the main manifestation, which can range from sullenness to grief, or even malaise, and in severe cases, psychotic symptoms such as hallucinations and delusions may occur. However, the beginning of the performance varies from person to person and cannot be stated exactly, often related to stressful events. The following ten manifestations can be used to initially determine whether the person is suffering from depression: 1. Depressed mood: often manifested as prolonged and obvious sullenness, depression and pessimism, no sense of pleasure, etc. In the face of things, work, even the work that used to be very much like, can be well done also do not want to do; 2, excessive low self-esteem: think that they are incompetent, useless, may appear helplessness and a sense of worthlessness; 3, slow thinking: can be manifested as thinking difficulties, for others to speak out or raise questions can not respond quickly, or even after a long time still thinking about the same problem, work and learning ability decreased; 4, will 4. Decreased volitional activity: it can be manifested as slow behavior, reluctance to contact and interact with others, laziness, etc., often living alone behind closed doors, alienating friends and relatives, etc.; 5. Decreased sleep quality: such as inability to sleep at night, short sleep time, shallow sleep, excessive dreaming, etc.; 6. 7. delusions: such as total fantasy of persecution, or condemning phantom content; 8. physical discomfort: such as headache, dizziness, nausea, loss of appetite, chest tightness, fatigue, constipation and other systemic symptoms; 9. decreased libido: some patients may experience decreased sexual function, male patients may experience impotence, female patients may experience irregular menstruation and menopause; 10. pessimism: serious pessimism, and in serious cases, even self-harm and suicidal tendencies may appear.