Commonly used antidotes for organophosphorus poisoning are cholinesterase revitalizers, cholinergic receptor blockers and compound preparations. 1. Cholinesterase resuscitator: commonly used drugs are chlorophosphorylphosphine, iodophosphorylphosphine and bisphosphonate. It can make the phosphorus in phosphorylated cholinesterase separate from the esterification site of cholinesterase and restore the activity of cholinesterase. 2. Cholinergic receptor blocking agent: mainly used for medium and severe poisoning, can relieve the symptoms of acute poisoning such as muscle fiber tremor, sweating, coughing. Commonly used are atropine, scopolamine, procyclidine, benactyzine and so on. 3. Compound preparation: it is the compound preparation of physiological antagonist and poisonous enzyme compounding drug, such as antiphosphorus injection (containing atropine, benactyzine, chloro-diphospholidine) and so on. Organophosphorus is mostly used in pesticides and insecticides, which are more toxic and are mostly seen in rural areas. Poisoning should be resuscitated immediately, and the use of specific antidote drugs should be under the guidance of a doctor.