1, syphilis is a sexually transmitted route of transmission, the other part is blood transmission. Usually hugging, kissing, eating will not be infectious. 2, regular treatment, after receiving penicillin drug treatment, the first year, every 3 months to recheck RPR + titer, the second year in June, the third year at the end of the year 3, short-term memory loss, dizziness and other mental symptoms, it is recommended to check the cerebrospinal fluid to exclude neurosyphilis