Patient: Description of the condition (onset, main symptoms, hospital visited, etc.): There is a papule at the scrotum, and sometimes there are unclear red circles on the forehead, suspected syphilis, 20 days of continuous azithromycin, 500mg, once a day, but not effective, and then went to the hospital for laboratory tests, the results are: RPR: 1:64+, TPPA: +. Stage II syphilis was diagnosed. He had syphilis once in 1998 but was cured. She is being treated with the following regimen: 3 million units of long-acting P-C injected intramuscularly four times a week, and at the same time, 8 drops of cephalexin 1g, one per day. Is this regimen feasible? Is it necessary to give four intramuscular injections along with 8 drips? If so, is a 7-day-a-week drip sufficient? Please advise! Thank you! Pang Chuanchao, Department of Dermatology, Second Hospital of Jilin University
Pang Chuanchao, Department of Dermatology, Second Hospital of Jilin University.
The choice of syphilis treatment plan
(1) Early syphilis: benzathine penicillin G 2.4 million U, divided into two sides of the buttocks intramuscular injection, once / week, 2 to 3 times in a row; or procaine penicillin G 800,000 U / d intramuscular injection, 10 to 15 days: penicillin allergic patients can choose ceftriaxone sodium 1 .Og / d static drip, 10 to 14 days in a row, or continuous oral tetracycline drugs (tetracycline 2.Og / d; doxycycline 200mg /d; minocycline 200mg/d for 15 days; or continuous oral erythromycin (erythromycin 2.Og/d) for 15 days.
(2) Late syphilis: benzathine penicillin G 2.4 million U, divided into two sides of the buttock muscle injection. 1 time / week, 3 to 4 times in a row; or procaine penicillin G 800,000 U / d muscle injection, 20 days in a row. Penicillin allergy can be used tetracycline or erythromycin drugs for 30 days, dose as above.