The reason why glomerulonephritis has a reduced filtration rate is due to the thickening of the glomerular filtration membrane and the formation of glomerular crescent. Glomerulonephritis includes acute nephritis, acute progressive nephritis, and chronic nephritis. The pathological type of acute nephritis is intracapillary hyperplasia, in which capillary endothelial hyperplasia leads to a thickening of the glomerular filtration membrane and a decrease in the filtration rate because water cannot be effectively filtered. The main pathological type of acute nephritis is crescent formation, and the glomerulus will be pressurized, and the filtration of water will be reduced, resulting in a lower glomerular filtration rate. Reduced glomerular filtration rate can cause water and sodium retention, leading to edema and increased blood pressure, which can be treated with diuretics, such as furosemide injection. If the filtration rate is significantly reduced and anuria has developed, this is treated with the help of hemodialysis.