Vigilance against drug-induced liver injury In recent January, the ward has consecutively admitted several patients with severe drug-induced liver injury, although all of them have turned out to be safe after careful treatment, they have caused great physical and mental harm and economic burden to the patients and their families. To this end, we are reminded: be alert to drug-related liver injury, safe use of medication, concise use of medication, carefully read the instructions of the drug, under the guidance of a doctor to use medication; put an end to the abuse of drugs, random use of medication; do not continue to use medication after the feeling is not right. Pharmacological liver injury, also known as pharmacological hepatitis, is caused by the use of a variety of drugs caused by the liver tissue acute or injury and dysfunction. In mild cases, it causes mild abnormalities in liver function, while in severe cases, it can quickly lead to liver failure, which is life-threatening. Since most drugs are metabolized and eliminated in the liver, liver injury caused by drugs is very common and accounts for 20-30% of all liver injuries. However, major injuries are often caused by our negligence. About more than 70% of drugs will affect liver function during normal use, some just increase the burden on the liver, some cause hepatotoxicity due to the accumulation of dosage by continuous use, and some drugs themselves have strong liver toxicity, but our liver is so powerful that a normal liver can provide for the use of 4 people, so we will not feel uncomfortable under normal circumstances. However, if the burden continues to worsen or the damage can not be repaired in time, or the particular drug comes into contact with idiosyncratic patients, it will cause severe hepatic tissue inflammation and necrosis, marked elevation of transaminases and serum bilirubin, manifested by obvious weakness, anorexia, severe yellow eyes, yellow urine, and even edema, coma and death. We admitted more serious patients in order of anti-tuberculosis drugs, skin disease drugs for psoriasis vitiligo (the so-called ancestral recipe is the most common), Chinese medicine for the treatment of lumbar, leg and arthralgia, and anti-tumor drugs. Once found that they may have drug hepatitis, timely to specialist hospitals to see a specialist, under the careful guidance of the doctor as soon as possible to control the development of the disease, if necessary, hospitalized for individual specific treatment. The treatment of drug hepatitis is divided into general hepatoprotective treatment, specific detoxification drugs, anti-inflammatory and anti-oxidative free radicals, protection of hepatocyte membranes, liver cell regeneration and other medical treatment, for the critically ill can be used as an artificial liver, the conditions allow liver transplantation.