Since 1998, more than 100 hospitals in the United States and more than 80 units in China have been equipped with argon helium knife equipment, which can perform precise cryosurgery for a variety of tumors and has made breakthroughs in the treatment of liver, lung, pancreatic, prostate, kidney, and breast cancers. Unlike other ablation methods, Ar-He knife freezing can treat small tumors as well as larger (>5cm in diameter) and more numerous tumors; due to the heat release effect of intravascular blood flow, freezing is less likely to cause damage to large blood vessels, so it can also treat tumors near large blood vessels that cannot be surgically removed. ”When argon gas is released rapidly in the tip of the needle, it can freeze the diseased tissues to -120℃~-165℃ in ten seconds; when helium gas is released rapidly in the tip of the needle, it will produce rapid rewarming and warming, which will quickly thaw the ice ball and eliminate the tumor. Moreover, the speed of cooling and warming, time and the size and shape of the ice ball can be precisely set and controlled.