The H. pylori treatment triad is a combination of three drugs used to eradicate H. pylori, which includes two antibiotics plus a proton pump inhibitor, used in combination to obtain better therapeutic results.1. Antibiotics: Two antibiotics are often chosen among metronidazole or tinidazole, clarithromycin, furazolidone, tetracycline, amoxicillin, and levofloxacin. If the penicillin is not allergic, the first choice is amoxicillin plus another antibiotic, because amoxicillin is less resistant to H. pylori. In case of penicillin allergy, tetracycline plus furazolidone is recommended. Attention should be paid to low doses of clarithromycin in elderly patients with combined coronary artery disease, and avoid levofloxacin in children; 2. Proton pump inhibitors: mainly including rabeprazole, esomeprazole, omeprazole, lansoprazole, etc. Triple therapy has the advantage of high eradication rate compared to single antibiotic therapy and diphtherapy. Because of the increasing drug resistance of H. pylori, the eradication rate of triple therapy is currently low in China. Clinically, quadruple therapy is recommended, which means adding a bismuth preparation to the above drugs, including colloidal bismuth pectin and bismuth potassium citrate capsules, and using the combination of four drugs for 10-14 days to eradicate H. pylori, the eradication rate will only be higher.