Gout is a disease caused by a disorder of purine metabolism, a disease of modern civilization, but also of ancient times. More than 400 years ago, Hippocrates, the father of Western medicine, and his disciples documented the characteristics of gouty arthritis in detail, but the cause was not yet known, except for speculation that the disease might be related to the deposition of certain toxic substances in the joints. It was not until 1776, when the Swedish chemist Scheele first isolated uric acid from a kidney stone in a gouty patient, and in 1797, when the English chemist Wollaston removed a gouty nodule from his own ear and isolated uric acid from it, that it was recognized that the toxic substance deposited in the joints and tissues was uric acid, and in 1824, when the English physician Garrod used chemical analysis to In 1824, Garrod, a British physician, measured high concentrations of uric acid in the blood of gout patients by chemical analysis, and pointed out that the key to gout was excessive production of uric acid, and from then on, people had a new concept of understanding gout. Although there is no diagnosis of gout in ancestral medicine, there is a description in the Yellow Emperor’s Classic of Internal Medicine, such as “the change of sorghum, the foot gives birth to a large ding”, pointing out that this disease is related to the over-eating of paste and thick taste. Gout has high blood uric acid and is accompanied by characteristic acute arthritic episodes. If the blood uric acid is only high without arthritis, it is called hyperuricemia, and gout occurs in 10-20% of hyperuricemia. We classify them into primary and secondary. The cause of primary gout is unknown and may be related to genetics, deficiency of certain enzymes in the body, and more and more modern reports indicate that primary gout is closely related to obesity, primary hypertension, dyslipidemia, diabetes mellitus, and insulin resistance. Secondary gout is mainly caused by kidney disease, blood disease, tumors, etc. Gout or hyperuricemia should also be checked to see if it is secondary. Gout is characterized by acute arthritis, which is often the first symptom of gout. The typical attack starts sharply, mostly waking up at midnight with severe pain, often in a single joint, with redness, swelling, heat and pain, joint effusion, and fever. The most common joint is the thumb-plantar joint, followed by the ankle, heel, knee, wrist, finger and elbow. Some patients with gout may have normal blood uric acid at the beginning of the disease, because blood uric acid fluctuates and should be checked several times. The common causes of gout are excessive fatigue, poor diet, excessive alcohol consumption, joint trauma, and excessive exercise. Gout is a disorder of purine metabolism, resulting in elevated blood uric acid, so the diet should pay attention to a low purine diet, such as animal offal, sardines, anchovies, eels, broth, etc., rich in high purine, to be prohibited, animal meat and spinach, beans sparse vegetables, etc., containing high purine, to control consumption. Gout patients should not drink alcohol. All kinds of alcohol can cause gout attacks for the following reasons: 1, ethanol in wine can directly accelerate the rate of purine synthesis in the body, increasing its production; 2, ethanol in wine can stimulate lactic acid synthesis in the body to increase, and lactic acid can inhibit the function of the kidneys to excrete uric acid, easily causing urinary stones; 3, some alcohol, especially beer in the fermentation process produces a large number of purines, which is very unfavorable to gout patients The gout is a chronic metabolic disease of the body. Gout is a chronic metabolic disease of the whole body, due to abnormal purine metabolism in the body, the blood purine metabolites – uric acid content increased. Once gout occurs, it is incurable, so it is important to pay attention to prevention and to change our lifestyles. Acute attacks: Colchicine is generally very effective, with symptoms usually starting to resolve 12 hours after treatment and disappearing completely within 36-48 hours. Colchicine should be administered at a dose of 1 mg orally every 2 hours until it is effective or until diarrhea or vomiting occurs. Non-steroidal anti-inflammatory drugs (NSAIDs) are effective for acute attacks of diagnosed gout. NSAIDs can cause many complications, including gastrointestinal upset, hyperkalemia (seen in patients who rely on prostaglandin E2 to maintain renal blood flow), and fluid retention. Patients at particular risk with NSAIDs include elderly patients, those who are dehydrated, and especially those with a history of renal disease. Prednisone can also be used for short periods of time, such as 20-30 mg/d. Occasionally, a combination of several drugs is needed to treat acute attacks of gout. In Chinese medicine, gout can be treated by paralysis and heat paralysis, such as Bai Hu Gui Zhi Tang or San Miao San with Lonicera, Loxodendron, Dioscorea, Che Qian Zi, Gentiana, Qin Pi, Xuan Hu, etc.