Pain relief within 1 hour for gout patients is clinically achieved through the use of medications, such as the use of colchicine, non-steroidal anti-inflammatory drugs, and glucocorticoids. All of the above drugs are recommended to be taken under the guidance of a doctor and may work within 1 hour, but they may not, with some individual differences. Patients with unbearable pain should first go to the hospital for more precise treatment by a doctor.1. Colchicine: It is recommended to be applied in small doses. Colchicine has anti-inflammatory and pain-relieving effects. Pay attention to adverse reactions when applying colchicine. Patients with gastrointestinal symptoms, such as abdominal pain and diarrhea after taking colchicine, suggest the presence of colchicine poisoning and need to stop the drug and go to the hospital in time; 2. Non-steroidal anti-inflammatory drugs: such as etoricoxib, meloxicam, loxoprofen sodium, celecoxib, ibuprofen, diclofenac sodium, etc., have anti-inflammatory and analgesic effects and act more rapidly. But for patients with peptic ulcer or active bleeding, the above drugs should be prohibited or used with caution; 3, glucocorticoids: In the acute attack of gout can choose to apply glucocorticoids, such as prednisone, betamethasone, hydrocortisone, dexamethasone, etc., can also be used for patients who can not tolerate colchicine, non-steroidal anti-inflammatory drugs. Glucocorticoids can reduce edema and congestion in joints, but they are prone to relapse after discontinuation, and long-term use can result in adverse effects such as peptic ulcers, infections, and osteoporosis. In addition, Chinese medicine believes that acupuncture treatment has a certain effect on relieving the pain during the acute attack of gout, which needs to be handled by a professional doctor.