The survival time of HPV in vitro is related to various factors such as temperature and humidity of the environment. It generally deteriorates around 56°C, survives 1-2 days at room temperature and 2-5 months at -20°C. HPV, the human papillomavirus, is highly infectious and resistant to heat and cold. HPV, the human papillomavirus, occurs in warm and humid environments, is resistant to cold and heat. HPV is highly infectious and is transmitted mainly through sexual transmission, contact transmission, and mother-to-child transmission. In terms of prevention, patients can disinfect the virus at high temperatures, which can be inactivated within seconds at 100°C. Therefore, patients should pay attention to wash their clothes separately in daily life to avoid infection as much as possible. In addition, patients with HPV infection usually have no clinical symptoms, so they should pay attention to improving their own immunity and avoid multiple sexual partners; at the same time, they need to take the initiative to go to the hospital for cancer prevention examination, and if they have symptoms of bleeding after sexual intercourse, they should seek medical attention in time, and their sexual partners should also be treated.