Yes, the liver not only regenerates, but it is the most regenerative organ in the body. This regeneration is a complex repair and compensatory response that occurs after liver injury (including partial resection and liver disease damage). Normal hepatocytes renew very slowly, but when the liver is damaged or partially removed surgically, mature hepatocytes can rapidly enter the cell cycle and regenerate through regeneration in order to compensate for liver function. Liver function can be fully restored by 2 weeks after two-thirds hepatectomy, and its volume and weight can eventually return to a level similar to that before surgery. However, abnormal livers that have undergone cirrhosis cannot regenerate completely normal hepatocytes. Factors that affect liver regeneration include blood supply to the liver, nutrition, age and medications. Liver regeneration is a precise and orderly process regulated by a variety of cytokines and hormones, and hepatocyte growth factor, as one of the powerful hepatocyte-developing agents, can initiate liver regeneration; insulin has a synergistic effect with it, therefore, the ability and speed of liver repair will be slowed down after liver surgery in patients with combined diabetes; in patients with combined cirrhosis, due to the large number of hyperplastic nodules slowing down the blood flow in the portal vein In patients with combined cirrhosis, the ability of liver regeneration and repair will also be slowed down after surgery due to the large number of hyperplastic nodules that slow down the blood flow in the portal vein and affect the circulation in the liver, as well as the weakened response of liver cells to cell regeneration factors.