Poisoning is usually the first thing to go to the emergency department, and it is common for poisonings to be food poisoning and heavy metal poisoning. Food poisoning may cause serious gastrointestinal damage, heavy metal poisoning may lead to organ failure. 1. After food poisoning, patients often manifest vomiting, diarrhea, abdominal pain, etc. If the diarrhea, vomiting aggravated may cause dehydration, severe dehydration will reduce renal blood flow and thus lead to acute kidney injury and other serious complications. Therefore, after food poisoning, you need to go to the emergency department at the first time to control the poisoning phenomenon in order to prevent complications. 2. Heavy metal poisoning is common for mercury, lead, copper and other poisoning, heavy metals can make the protein structure irreversible lesions, so that the function of tissue cells are affected, and at the same time, after poisoning due to the toxicity of heavy metals, it will make the body blood circulation obstacles, resulting in renal circulatory dysfunction and thus causing renal failure. To summarize, poisoning may cause a variety of serious damage to the organism, and it is recommended that patients stay away from the poison immediately and go to the emergency department to control the symptoms of poisoning and reduce the toxic reaction in time.