Cryptogenic nephritis and IgA nephropathy are different in terms of nature, symptoms and the way the condition is detected. Occult nephritis is a clinical diagnosis, mainly manifested as abnormal urine routine, no discomfort symptoms, insidious onset, not easy to detect; IgA nephropathy is a pathological diagnosis, manifested as a large amount of proteinuria, hematuria, usually with hematuria onset. 1. Nature: cryptogenic nephritis is a clinical diagnosis, which is a clinical classification of glomerular diseases; IgA nephropathy is a pathological diagnosis, which is characterized by the deposition of IgA immune protein globules in the glomerular tunica albuginea. 2. Symptoms: Cryptogenic nephritis is usually manifested as asymptomatic hematuria and asymptomatic proteinuria; IgA nephropathy is usually accompanied by a large amount of proteinuria, hypertension, edema and other symptoms. 3. How to find out the disease: cryptogenic nephritis is not easy to detect, usually found in routine urine examination; IgA nephropathy is usually accompanied by hematuria or microscopic hematuria, accompanied by varying degrees of proteinuria, and the disease is in chronic progressive development. When kidney disease occurs, it is necessary to consult a doctor in a regular hospital in time to clarify the cause of the disease and treat it as soon as possible to avoid aggravation of the symptoms and affecting your health.