The early stages of gout are mostly asymptomatic, with no discomfort and only a persistent or fluctuating increase in blood uric acid. Many patients do not even know that their blood uric acid is elevated without a blood test. The asymptomatic phase of gout can last for years or decades and is associated with a number of factors, including gender, age, history of hyperuricemia, and blood uric acid levels. The acute arthritic phase of gout begins when the red, swollen and painful joints start to appear, with sudden onset of red, swollen and painful single joints as the main manifestation, mostly at night or in the morning during sleep. The first attack is common in the joints of the feet of the lower limbs, the first metatarsophalangeal joint is the most common, but can also spread to the knees, fingers, wrists, elbows and other joints. Patients often feel the pain and swelling of the joints as if they were cut or bitten by insects. These joint symptoms can also resolve on their own within a few days or 2 weeks or with medication. If the disease is not well controlled, frequent attacks of acute gouty arthritis may cause chronic joint inflammation, resulting in persistent joint swelling, pain, and even joint deformity, affecting joint function. Long-term hyperuricemia can also cause the deposition of urate crystals in various parts of the body to form gout stones, which can also be deposited in the kidneys and cause gouty nephropathy, leading to symptoms such as hematuria, proteinuria, edema, anemia, hypertension, and renal colic. As the disease progresses, acute gout attack symptoms such as sudden single joint redness, swelling and heat pain may occur.