Symptoms of eating puffer fish poisoning include numbness, nausea, motor paralysis, slurred speech, cyanosis, weak heartbeat, etc., which need to be differentiated according to the degree of mild, moderate, severe and extremely severe. 1. Mild: patients will only experience numbness of lips, tongue and fingers, as well as nausea, vomiting, diarrhea and other discomforts. 2. Moderate: On the basis of mild symptoms, the numbness further develops into paralysis of fingers, upper and lower limbs movement. 3. Severe: the patient will develop generalized motor paralysis, as well as slurred speech, cyanosis, skeletal muscle flaccidity and weakness, difficulty in swallowing, drop in blood pressure and other symptoms. 4. Extremely severe: patients will have shock manifestations such as weak heartbeat, unconsciousness and respiratory arrest. Usually, if the condition of puffer fish poisoning is mild, it can be cured by taking standardized treatment in time, but if the intake of toxin is more and the treatment is not timely, it will be life-threatening. All in all, puffer fish poisoning people need to go to the hospital in time, cooperate with the doctor active treatment, so as not to delay the condition.