Depression is a common psychiatric disorder in clinical psychiatry. Depression can also bring about many physical symptoms, such as insomnia, panic attacks, palpitations, chest tightness, shortness of breath, headache, dizziness, or accompanied by gastrointestinal symptoms, such as nausea, vomiting, diarrhea, constipation, male patients may experience sexual dysfunction such as frequent urination, urgent urination, impotence, premature ejaculation, and female patients may experience gynecological disorders similar to menstrual irregularities and menstrual disorders symptoms. If somatic symptoms appear, we must pay enough attention to them, and need to go to the psycho-psychiatry department for clear diagnosis, and choose psychotherapy, cognitive-behavioral therapy or antidepressant medication, such as fluoxetine, citalopram, duloxetine and other drugs to help adjust according to the change of the severity of the disease.