The presence of calcification inside the breast nodule suggests a possible malignant nodule, usually caused by the deposition of calcium salts inside the nodule, and requires a breast ultrasound and mammography to determine the benignity or malignancy of the nodule. If a malignant nodule is suspected, it can be found to have low echogenicity, unclear borders, internal calcifications, or abnormal blood flow signals inside the nodule. If necessary, a small amount of tissue can be taken for pathological examination by a coarse needle puncture, or a complete removal of the breast nodule under local anesthesia can be sent for pathological examination before a clear diagnosis can be made. If the diagnosis is breast cancer, surgery is required. After surgery, the next step of treatment will be decided based on the results of pathological examination.