Headache after taking sildenafil is mainly related to adverse drug reactions. If the headache symptoms are not very obvious need to observe, most of the symptoms subside quickly. If there are obvious and severe side effects, there are visual color changes, increased sensitivity of the eyes to light and blurred vision, it is recommended that ibuprofen needs to be taken under the guidance of a physician to improve the headache, and if the symptoms persist without relief, a hospital visit is required. If sildenafil drug overdose poisoning occurs, there are no special effective interventions, mainly conventional supportive therapy is taken, the binding rate of sildenafil and plasma protein is relatively high, and performing renal dialysis is also not too good for sildenafil concentration overdose. It is recommended to avoid taking sildenafil in general, especially for heart disease or elderly patients to be applied with caution to avoid causing adverse reactions.