Neck masses account for about 3-4% of the total body masses, including inflammatory diseases (lymph node tuberculosis), congenital diseases, benign tumors and malignant tumors. Patients presenting with neck masses require proper diagnosis and timely management. Because thyroid masses are mostly benign and have their own characteristics, they are not included in the discussion of neck masses. The “7” and “80%” rules proposed by Skandalakis are useful for the initial identification of neck masses: those with onset within 7 days are mostly inflammatory, those with onset between 7 weeks and 7 months are mostly tumors, and those with onset more than 7 years old are tumors. Those with onset of 7 weeks to 7 months are more likely to be tumors, and those with onset of more than 7 years are more likely to be congenital malformations. Treatment: 1. Inflammatory mass: anti-infection, abscess (except cold abscess) can be incised and drained, cervical lymphatic tuberculosis should be looked for tuberculosis foci in lung and intestine, and treated with anti-tuberculosis drugs. 2.Congenital congenital masses and benign tumors: they can be surgically removed, and hemangiomas can be treated with sclerosis injection, laser, freezing, etc. 3.Malignant tumor: 1.Primary malignant tumor: according to the site, pathology, and the presence of metastasis, surgery, radiotherapy, chemotherapy or comprehensive treatment are used. 2.Metastatic malignant tumor: ①Cervical lymph node metastasis with primary foci in the head and neck can be treated with combined radical surgery, radiotherapy and/or chemotherapy. ②Cervical lymph node metastasis with primary foci below the clavicle: generally only chemotherapy is applicable. While malignant tumors with primary foci in mediastinum and esophagus or sensitive to radiotherapy, radiotherapy can be considered for both primary foci and metastases. ③Cervical lymph node metastasis with unknown primary focus: In order to control the development of metastases to prolong the survival of patients, aggressive treatment can be considered and the primary focus can be continued to be found during the treatment.