In recent years, with the continuous development of social and economic development, the large flow of young and middle-aged labor force in the sexually active period, coupled with the change of life and values, marital relationship instability is becoming more and more serious, resulting in the annual incidence of STDs in China has increased year by year, of which, according to statistics, the number of incidence is the first syphilis. The vast majority of people lack a correct understanding of STDs and are very frightened when it comes to syphilis or are ashamed to talk about it or cause family conflicts, frightened that syphilis will immediately endanger life, worried about the cost of treatment is very expensive and do not dare to go to the hospital to receive regular treatment, resulting in serious consequences. Don’t be anxious, patiently read the following syphilis basic knowledge, you will suddenly understand, the original syphilis is so! I, first of all, the diagnosis of syphilis Clinical often encounter such a situation, the original very harmonious family is immersed in the joy of welcoming a small life, but get a bolt from the blue, the pregnancy test found that the mother-to-be has syphilis, so the in-laws complaints, the husband’s disbelief, the wife’s grievances are stirred together ……. Of course, there are also adult children with elderly father or mother around the bend to tell the doctor that “mother or father has been dead for many years, and the surviving father or mother is also at home for a long time due to illness, how will the *** hospital check has syphilis, the family used to eat and sleep together will not be infected to others. In fact, the above two excessive worry are unnecessary, because the test results themselves due to the limitations of the patient’s own condition there are many false positives and false negatives. Syphilis is a disease caused by syphilis spirochete infection that is mainly sexually transmitted and can invade all systems of the body. Its clinical manifestations are called “mimics” by dermatologists because of its diversity. Due to the limitations of the testing equipment and testing environment, the current diagnosis mainly relies on immunoserological testing. The test includes syphilis spirochete specific antibodies and syphilis spirochete non-specific antibodies. With the current level of testing, the former is often given as a quantitative indicator (also known as titer) (RPR), and can therefore be used as an indicator of efficacy when reviewing syphilis after treatment; the latter is only a qualitative result (TPPA), which is essential for the first test to confirm the diagnosis of syphilis. Many hospitals only test for one of these tests as a screening test for syphilis due to limitations, but a positive result for any of these two tests alone cannot diagnose current syphilis. Factors affecting the test results include systemic lupus erythematosus, rheumatic heart disease, arthritis, liver cirrhosis, colon cancer, intravenous drug use, pregnancy, old age, diabetes, etc., and acute and chronic infectious diseases such as rubella, filariasis, and tuberculosis. Our hospital applies three methods to test two antibodies at the same time, in order to give you a correct diagnosis from a scientific point of view. The specific details of the test results need to be explained by a professional doctor, do not let some false positive results disrupt your happy family; in addition, for the first syphilis serology test can be negative, but you have not been infected with syphilis spirochetes thrown need to be a comprehensive judgment of professional doctors, so when you have concerns in this regard do not just do not know what to do, but should be timely to the regular hospital to receive regular diagnosis and treatment. Second, the symptoms of syphilis Phase I syphilis mainly shows a single or disseminated several shallow ulcers near the genitals, or inguinal lymph nodes swollen, but a significant number of patients do not have any symptoms and directly into the next phase. The rash of stage II syphilis is a universal imitator, it can resemble any skin disease and the diagnosis still requires the experience of a specialist, but of course there is still a significant proportion of people who have no symptoms at this time. Stage III syphilis About 40% of untreated syphilis patients can develop active late syphilis, which can invade any of the organs such as joints, bones, eyes, cardiovascular and nervous system in addition to skin and mucous membrane manifestations, seriously endangering the health of patients. Third, pregnancy syphilis and congenital syphilis Not syphilis pregnant women can not produce. The syphilis spirochete is not transmitted to the fetus through the placenta five years after the woman herself is infected with syphilis. In patients with current syphilis, the syphilis spirochete cannot pass through the placental barrier during the third month of pregnancy, and as long as they receive regular syphilis treatment at this time, more than 95 percent of pregnant women can give birth to healthy babies. Of course, if you miss this time, you can still treat the fetus during the 7th-9th months of pregnancy. As long as the congenital syphilis patient does not have serious organ damage, if the serology is only positive, after birth to give regular syphilis treatment, often very good results! Fourth, syphilis transmission 95% of syphilis is through sexual relations, mother to child and blood transmission. Because the semen, vaginal secretions, saliva, milk, rashes and mucosal exudate, blood and even sweat of syphilis patients contain enough infectious amount of syphilis spirochetes (minimum about 50), so syphilis is more infectious than hepatitis B, C, AIDS, etc., more ways of transmission. It is not uncommon for people to become infected through close contact with patients, such as breastfeeding, kissing, or using utensils or household items contaminated by patients (body fluids, blood and secretions). It is also not uncommon for medical personnel to become infected with syphilis themselves because of occupational exposure. At present, the spread of syphilis has spread to the general population. V. Treatment of syphilis The treatment of syphilis is valuable in the standard, it is reported that early syphilis after standardized adequate treatment, about 90% of early patients can achieve the purpose of eradication, and the earlier the effect of treatment, the better. It should be emphasized that syphilis should not be treated indiscriminately, because only 25% of untreated early syphilis end up with serious damage, while 35%-40% of those who receive inappropriate treatment have worse results than those who are not treated, indicating that irregular treatment can increase recurrence and promote the early occurrence of late damage. Penicillin is still the drug of choice for all stages of syphilis.