Antidepressants are not addictive substances. There are two criteria for addiction: 1) psychological addiction: i.e. a strong psychological craving for the use of drugs, to the extent of recklessly looking for drugs to eat; 2) body addiction: manifested by the inability to break the drug, otherwise life-threatening withdrawal reactions occur, and also manifested by taking more and more, and not being able to achieve the original sought-after effect with the original dose. Obviously, not wanting to take medication indicates that there is no heart addiction; antidepressants are generally reduced in the maintenance period, which is also not in line with body addiction. In order to avoid “withdrawal reactions” when antidepressants are suddenly stopped, it is advisable to stop taking them gradually and slowly. Studies have shown that long-term use of antidepressants can not only prevent relapse, but also help protect neurological function and improve cognitive and somatic function.