In clinical diagnosis and treatment, since many treatment principles of hepatitis B involve very specialized medical knowledge, it would be very difficult to communicate with patients in these specialized languages, but if we use some easy-to-understand language to visualize the abstract hepatitis B diagnosis and treatment knowledge, patients will be very easy to understand, their compliance will be good, and the treatment effect will also become better, so we decided to take time to do some lectures on I hope to provide some useful knowledge to the majority of liver disease patients and take less detours in the fight against the disease. Hepatitis B virus is the DNA virus that causes acute and chronic hepatitis in humans, referred to as HBV, is the culprit that causes hepatitis B. It has the following characteristics: 1. Hepatitis B virus (HBv) has a tenacious resistance: it can tolerate heat, low temperature, dryness, ultraviolet light, the general concentration of chemical disinfectants; at -20 degrees Celsius can not freeze it, can live 20 years! It can survive 6 months at 30-37 degrees, 7 days at more than 37 degrees, and 6 hours at 55 degrees. HBv is very sensitive to 0.5% peroxyacetic acid, which is a strong oxidizer and can kill them. 3% bleach, 0.2% Neosporin can also be used to kill HBV. 2, HBV has obvious hepatophilia: HBv is also called hepatophilic virus. It is because it invades the human body to specifically attack the liver, drilling into the liver cells, where they settle and reproduce. According to research, this is because there is a HBv “receptor” on the surface of the liver cells, accepting HBv. a large number of HBv concentrated in the liver cells, constantly multiplying, replicating, mature HBv is released from the liver cells, and invade other healthy liver cells, so constantly replicating, constantly invading, and eventually induced immune damage to the liver cells. 3, HBV also has a mild “panophilia”: although HBv has hepatophilia, but it also has a certain “panophilia”! The so-called “panophilia” is that HBv occasionally invades organs and tissues other than the liver, such as bile duct epithelial cells, renal tubular cells, cells of the pancreas, gastric mucosal cells, blood mononuclear cells, etc. Therefore, HBv can sometimes cause diseases in the above areas, such as HBV-associated diabetes, HBv HBv-associated nephritis, HBv-associated gastric disease, HBv-associated hematologic disease, etc. But these “panophilic” attacks do not necessarily occur, most people infected with HBV do not occur “panophilic” damage, so it is said to be mildly panophilic, HBv is still mainly invasive of the liver. 4, HBv’s strict species characteristics: that is, HBv is mainly invasive of humans and other primates, so far, only humans, chimpanzees, gibbons, baboons to HBV easy to infect, other animals will not be infected with HBv. although blood-sucking insects may find traces of HBv, but only temporarily “host” has been, generally will not be in their bodies. Although traces of HBv may be found in blood-sucking insects, they are only temporary “hosts” and generally do not replicate and multiply in their bodies. People often contact animals such as chickens, horses, cattle, sheep, pigs, dogs, etc. can not spread HBv. 5, the chronic nature of HBv infection: China’s existing HBv carriers 120 million people, they are HBv chronic infection. Studies have found that almost all of these people are infected with HBv in fetal life or early childhood, after a decade or even decades of infection, HBv is still in their body does not disappear, but also does not develop. However, they can still constantly discharge HBv to the outside world, is an important source of hepatitis B infection. 6, the mutability of HBv: scientists have found that HBv is one of the most mutable viruses. The so-called mutation, is the genetic mutation of HBV, mutation is also the virus in order to their own survival “strategy”, if there is a strong anti-HBV drugs into the body, is bound to pose a threat to the life of HBv, in order to resist the role of drugs, they will make their own “mutation “. HBv mutation characteristics to the diagnosis and treatment bring many problems. 7, HBv itself is non-pathogenic to the liver: see here, you may be confused, HBv clearly has hepatophilia, specifically damage the liver, how and no pathogenicity to the liver? It is really strange that HBv does not have a direct toxic effect on the liver, and it has been proven that a large number of HBv carriers in China have a lot of HBv in their bodies, but do not develop hepatitis. If HBV could directly damage liver cells, then these asymptomatic HBv carriers would not exist and would all be hepatitis B patients. It turns out that the onset of hepatitis B is due to the body’s own immune system, such as immune cells are not involved, HBv will not cause liver damage. 8, the carcinogenicity of HBv: now it has been affirmed that HBv is an important factor in causing liver cancer, about 80%-90% of liver cancer have HBv background. It has been observed that about 5-10% of people with a 20-year history of HBv infection become cancerous, and the cause of cancer is the integration of the x-gene of HBv into the genes of liver cells and mutations occur, leading to liver cancer. The most important concern is also the problem of HBV carcinogenesis. Especially asymptomatic HBv carriers are most afraid of cancer. In fact. Most liver cancers occur on the basis of chronic liver disease, especially cirrhosis, and the liver of HBV carriers basically has no inflammation, let alone cirrhosis, so generally the foot will not become cancerous directly, so we don’t need to worry too much. The hepatitis B virus itself does not cause direct harm to the human body, hepatitis is the result of the interaction between the virus, the body and the immune system. 2, existing research shows that eating together, sharing utensils does not spread hepatitis B, hepatitis B is mainly transmitted through the blood 3, not every hepatitis B patients will embark on hepatitis B three parts: hepatitis, liver cirrhosis, liver cancer. As long as they receive timely and regular treatment, most hepatitis B patients can live like normal people.