Cerebral atrophy is a reduction in the volume of brain tissue, brain parenchyma, brain weight, cell count, flattening of the gyrus, widening and deepening of the sulci, and enlargement of the ventricles, brain pools, and subarachnoid space caused by various causes. According to the location and extent of brain atrophy, brain atrophy is divided into cerebral, cerebellar, olivary, and pontine atrophy, limited and diffuse atrophy, cortical and central atrophy. Cerebral atrophy is a chronic mental decline disease. It is characterized clinically by memory impairment, emotional disturbances, changes in personality and behavior, and diminished intelligence. Cerebellar, olivary, and pontine atrophy is a chronic progressive disease characterized by ataxia. It is characterized by unstable gait, dysgraphia, limb tremors, slurred speech, and skeletal deformities. In Chinese medicine, it is known as unstable walking when the foot can reach, unstable grasping when the hand can lift, stumbling gait, clumsy movements, and speech blurring, or head shaking, tremor, or spasm. What are the manifestations of delayed cerebellar cortical atrophy syndrome? This syndrome is usually autosomal dominant, and the lesions mainly affect the cerebellar hemispheres, earthworms, choroid, and olivary degeneration and atrophy, while the brain, midbrain, cerebral bridge, and medulla are normal. The onset of the disease is late, mostly at the age of 50-60 years, with a rapid onset and slow progression. The disease starts with ataxia of the trunk, followed by ataxia of both lower limbs, unstable walking and standing, and relatively mild symptoms of the upper limbs. Tendon reflexes are weakened or absent, dysarthria, resting tremor of the head and trunk, and nystagmus appear at a later stage. Acupuncture, physical therapy, and somatic therapy can improve symptoms, and care should be taken to avoid respiratory and pulmonary infections. The disease generally does not affect life expectancy and most deaths are due to complications.