Liver disease remains a heavy health burden and one of the top five causes of death, and the incidence of liver disease and its associated deaths show no signs of abating. The main reason for this is the rapid increase in the prevalence of fatty liver disease associated with obesity, diabetes and alcohol abuse, which has replaced viral hepatitis as the most important chronic non-communicable disease and poses a serious risk to human health and social development. The prevention and treatment of fatty liver disease involves many fields of preventive medicine and clinical medicine, such as gastroenterology, endocrinology, cardiovascular, infection, nutrition, imaging, and exercise rehabilitation, etc. The assessment of the condition and risk of fatty liver disease and the development of treatment plans require multidisciplinary collaboration.