Poor mood first affects the central nervous system such as the brain, and then affects the vegetative nervous system, the endocrine system and the immune system, and through the intermediary of these systems, finally causes lesions in the internal organs, thus leading to psychosomatic diseases. The etiology and pathogenesis of dysphoria may be related to psychological factors, social factors, etc. It is also believed that it is a protective response of the body to acute stress. Poor mood should be noted and the following symptoms differential diagnosis: 1, depression: Depression (Depression) is a form of manic depression episodes. Typical symptoms are depressed mood, slowed thinking, and reduced speech and movement, and retardation. Depression seriously disturbs the life and work of patients and brings heavy burden to families and society, and about 15% of depressed patients die by suicide. A joint study by the World Health Organization, the World Bank and Harvard University shows that depression has become the second most common disease burden in China. Factors that cause depression include: genetic factors, physical factors, abnormalities in the function and metabolism of central nervous mediators, and psychiatric factors. 2, mental aging: modern scientific research on mental health points out that the physical appearance of people, physical functions with the age of old age, can become old and declining, this is a natural law, human beings can not be reversed. But psychological aging can not be, to always feel youthful, vibrant and confident.” Let the elderly always feel youthful” is a true saying that is pertinent to the time. The physical aging of human body cannot be controlled and changed, but the psychological aging of human body can be self-regulated and controlled, which is the result of subjective initiative and self-psychological care. Psychological aging makes people accelerate the physical decline, depression, disease, lack of joy in life, become small and inferior, do nothing, and seriously damage the health and longevity of the elderly. This is a big taboo for the elderly self mental health care. 3, serious emotional disorders: serious emotional disorders, refers to long-term emotional or behavioral reactions significantly abnormal, seriously affect the adaptation of life; its disorders are not due to intelligence, sensory or health factors directly caused by the results. The symptoms of mood disorders include mental disorders, emotional disorders, anxiety disorders, attention deficit hyperactivity disorder, or other persistent emotional or behavioral problems. 4, temperamental: In our daily life and work, we can often see some temperamental people. Irritability is a kind of mania, which is rooted in restlessness and can lead to mental disorders if allowed to develop. “Irritability” is a disease, sometimes energetic, the sky is free, and sometimes depressed, at a loss. Many teenagers often appear the above phenomenon, experts say, this is a “bipolar disorder”, also known as bipolar disorder. 5, useless feeling: useless feeling is common in the elderly after retirement and endogenous depression. Retirement syndrome of the elderly is a complex psychological abnormal reaction, mainly in the mood and behavior. Patients with endogenous depression are often accompanied by strong feelings of self-blame, guilt, and uselessness, and view their past, present, and future in a negative light. Poor mood generally does not require specific treatment, but family members should help the patient through this phase. Psychotherapy is given appropriately to eliminate anxiety. Previous history of affective disorder neurotic depression and other medical conditions should be taken as a precaution to try to avoid the occurrence of postpartum dysphoria or its development into postpartum depression and postpartum psychosis.