Which patients with primary liver cancer are suitable for ablation therapy? Currently, radiofrequency ablation therapy is the most clinically used and most effective. Ablation therapy for the purpose of radical treatment is mainly applicable to liver tumors less than 3 cm, while the number of lesions generally does not exceed 3. Radiofrequency ablation therapy meeting the above conditions can achieve similar therapeutic effects as surgical resection. Three issues are crucial in percutaneous percutaneous radiofrequency ablation of liver tumors: the first one is the accuracy of tumor localization and guiding puncture. The accuracy of the puncture directly depends on the experience of the doctor and the superiority of the equipment; another important factor is the localization of high temperature sufficient to kill the tumor; the last issue is the tumor located at the edge of the liver, the liver is located in the abdominal cavity, and the surrounding adjacent organs include the diaphragm, stomach, duodenum, gallbladder, colon, right kidney and adrenal gland as well as the abdominal wall structures, radiofrequency ablation of the tumor at the edge of the liver can easily damage the Radiofrequency ablation of tumors in the liver margin can easily damage the above mentioned adjacent structures and organs, thus causing more serious complications. For the latter two cases, open surgery or laparoscopic surgery can be used to block the blood flow of the adjacent blood vessels and separate and protect the adjacent structures and organs, thus solving the limitations of percutaneous percutaneous radiofrequency ablation. Of course, patients undergoing ablation must be physically able to tolerate it, and must meet certain requirements for physical condition, liver function, and coagulation, which are slightly more lenient than those for surgical resection, so please consult your treating physician for details. Like surgical treatment, ablation is a local treatment and requires limited lesions. If the tumor has spread and metastasized or there are too many lesions, this treatment is not suitable. How to judge the efficacy of primary liver cancer after ablation treatment? What should be noted after treatment? Whether the tumor is completely inactivated after radiofrequency ablation treatment for liver cancer, that is, whether the tumor is completely “burned”, is the main concern of doctors and patients and their families. The most important method to determine whether the tumor is completely inactivated is the enhancement imaging examination. If necessary, 2 or even all 3 of these examinations need to be done to corroborate each other and improve the accuracy of judgment. For patients with elevated tumor markers before ablation treatment, the decrease of tumor markers after treatment is also one of the indicators to assist in the judgment. Generally speaking, these tests should be performed about 1 week to 1 month after ablation treatment. If the ablation effect is not satisfactory, additional ablation treatment can be performed. Patients who have achieved satisfactory curative effect should undergo review at least every three months, because recurrence of liver cancer is very common, and regular review can detect problems early and provide early treatment. In addition to timely efficacy evaluation and review, patients who have just undergone ablation therapy need to pay attention to the possible complications of ablation therapy. If ablation treatment damages the adjacent digestive tract (e.g. gallbladder, colon, etc.), which may cause more serious complications, such as perforation of the digestive tract, diffuse peritonitis, etc., it is necessary to seek medical attention as soon as possible.