Acne is caused by multiple factors, which may be related to genetics, high androgen levels, unstable hormone levels, surface bacterial colonization, immune response, emotions, etc. 1. The pathogenesis of acne is not completely clear. It is a local inflammation of the sebaceous glands of hair follicles, which are regulated by sex hormones. High androgen levels are easily caused, so high androgen levels in the body after puberty are prone to occur. In women with polycystic ovaries or premenstrual periods, androgen levels increase and acne is also likely to occur. You can use some spironolactone to reduce androgen levels and improve menstrual acne. 2, acne with Propionibacterium acnes reproduction has been recognized by the industry, the bacterium is the main acne pathogen. 3, patients with high oil secretion and easy blockage at the hair follicles are also good causes of acne. The intake of too much sugar or oil will intensify the blockage and should be actively avoided by eating more fresh fruits and vegetables. 4, Staying up late and having an irregular life for the same reasons as 3, while causing endocrine disorders, will aggravate acne. 5, some patients may be related to emotions, emotional excitement, tension also tend to aggravate acne. 6. Whitehead acne and adult acne may be related to improper use of skin care products, especially powder skin care products, and attention should be paid to facial cleansing and moisturizing. The causes of acne are complex, so it is difficult to treat and easy to repeat. You should combine your situation to find the triggers and use medication reasonably.