Infantile hemangioma is the most common type of hemangioma among newborn infants and children. Infantile hemangiomas belong to the category of vascular tumors, which have a fixed growth cycle. They are found within 1-2 weeks after birth and grow rapidly in the first year (80% of hemangiomas stop growing around 5 months of age and reach their maximum size by 1 year of age at the latest), and then enter a slow receding period which usually lasts until 5-10 years of age, or even longer in some cases. 1.General: The course of infantile hemangioma can be divided into three periods: the growth period, the quiescent period and the receding period. The total incidence of hemangioma is about 1% to 12%, and the incidence is high before the age of 1 year, reaching 10% to 20%. The incidence rate is three times higher in girls than in boys, and the incidence rate is higher in premature and low birth weight infants than in normal fetuses. The vast majority of hemangiomas appear after birth or within 1 week after birth. Clinical manifestations Infantile hemangiomas tend to occur on the head and neck (60%), followed by the trunk (25%) and extremities (15%), and the vulva is also one of the most common sites. The majority (80%) of hemangiomas are solitary, with a few being segmental, indeterminate, and multiple. Even in multiple hemangiomas, the number of hemangiomas is often less than 10. In infants and young children, hemangiomas usually appear initially as dilated capillary spots, pale white spots, erythematous spots surrounded by a white halo, and in some cases as bruises or scratches. During the growth phase, the manifestations vary and are mostly papules, nodules, and plaques with red color. During the regression phase, the central part of the lesion first becomes lighter in color and less hard, and then the whole hemangioma gradually becomes lighter, flatter and softer. Complications About 40% of infants and children with hemangioma can have complications, and the occurrence of complications varies depending on the location, size and growth rate of the tumor. Complications can be functional or organic, such as ulceration, bleeding, infection, heart failure, impaired vision, airway obstruction, feeding difficulties, and external ear canal obstruction. Urea is a normal metabolic product of the human body and has no obvious toxic or side effects on the body. High concentration of urea can make the diseased endothelial cells of blood vessels shrink and degenerate. At present, local injection of urea for the treatment of infant hemangioma (strawberry hemangioma) is the characteristic treatment method of the Department of Hemangioma of Henan Provincial People’s Hospital, which has no toxic side effects for children. The treatment methods such as laser (local tumor and skin damage, easy residual scar) are relatively simple and effective, and will not leave a scar.