A cure for liver failure is possible. Patients with liver failure are rapidly progressive, difficult to treat, and have a poor overall prognosis. Among them, acute liver failure has the highest mortality rate, with subacute liver failure and chronic liver failure having decreasing mortality rates in that order. Patients with liver failure induced by alcohol consumption and drug-induced liver injury have a relatively good prognosis, while those with liver failure superimposed on the basis of chronic liver disease or compensated cirrhosis have a poor prognosis. If liver failure can be treated with active symptomatic support, it is possible to recover gradually, depending on the degree of hepatocyte necrosis and the regenerative capacity of hepatocytes. If the hepatocytes regenerate in large numbers, exceeding the necrotic cells, liver failure can be gradually recovered. If there is extensive necrosis of liver cells, the residual liver cells are unable to compensate and the patient eventually leads to death. In addition, with the maturation and promotion of liver transplantation technology, the survival rate of liver failure patients has improved significantly, and there are reports of liver transplantation patients who have survived for more than 20 years. However, the only disadvantage is the lack of liver sources and the high cost, resulting in many patients not being able to receive timely surgical treatment.