What is hormone dependence? Hormone dependence is caused by the long-term topical application of glucocorticoid preparations and the development of dependence of the affected skin on the drug. Hormonal dermatitis is a non-purulent inflammation of the skin caused by the improper or abusive use of topical hormone preparations. What are the characteristics of hormone dependent dermatosis? 1. The original disease improves rapidly after medication, but cannot be cured; 2. After treatment lasts for weeks or months, once the medication is stopped, erythema, papules, tenderness, fissures, pustules, desquamation, pain, itching, burning, tightness, and deterioration of the original disease occur within a few days; 3. When topical hormones are reapplied, the above symptoms quickly subside, and if the medication is stopped again, rebound dermatitis occurs rapidly and is heavier than before; 4. To avoid the pain of rebound dermatitis reoccurrence after discontinuation, they rely entirely on topical hormones. Some of the original topical preparations are not effective and must be replaced with stronger hormonal topical preparations, or increase the dosage, or shorten the interval between medications in order to improve symptoms; 5. The amount of medication used in treatment is proportional to the length of the disease, the longer the disease, the more medication is used, the more severe the condition. What are the side effects of hormone dependence? 1. The main manifestation is the recurrence of the disease, acne-like changes, persistent dry skin, increased sensitivity and discoloration; 2. After moderate to severe hormone dependent dermatitis reaches clinical cure, secondary hyperpigmentation will appear, which brings a great mental burden to patients, especially women who occur in the facial area. Why does hormone dependence on the face tend to occur in women? The proportion of female patients with hormone dependent dermatitis is much larger than that of male patients. Among female patients, except for some who have a clear history of topical hormone drugs, the rest have a clear history of topical cosmetic use, especially the history of topical use of efficacious cosmetics, although they do not have a history of topical drug use, and all of them show facial dermatitis and acne after stopping or using for a period of time. The lesions did not subside on their own. Therefore, it is presumed that the addition of hormones in cosmetics is another important cause of facial hormone dependence dermatitis, especially the highest incidence of hormones in efficacious cosmetics, which is also the reason for the significantly higher incidence of facial hormone dependence dermatitis in women compared to men. How to treat hormone dependence? 1. There is no special treatment for hormone dependence, and the principle of treatment is mainly local protection and soothing, and more importantly, promoting the self-renewal role of the skin. Due to the long time of epidermal passage, coupled with the hormone induced epidermal nutritional disorder and impaired epidermal barrier function, the recovery of this disease is slow. At present, the efficacy of combined Chinese and Western medicine methods in treating this disease is certain; 2. During the treatment process after stopping the use of hormone preparations, patients repeatedly have hormone rebound symptoms, as few as two or three times, as many as five or six times, and it takes at least two months, as many as two years, to reach clinical cure, and the cure time is proportional to the strength and time of the patients’ topical hormone preparations; and the skin still exists after the complete disappearance of the patients’ facial lesions The patient’s skin sensitivity is still high after the complete disappearance of the facial lesions, and it still takes longer to recover completely; at the same time, secondary pigmentation is also a problem that exists after the patient is cured. Therefore, the treatment time of hormone dependent dermatitis is long, the efficacy is not significant, the patients are under great psychological pressure and have many problems. Spicy and stimulating diet, seafood, fish and shrimp, mutton and other hot foods should be avoided.