Patient: Description of disease (onset time, main symptoms, hospitalization, etc.): Patient: male 51 years old, now without any pain, anorexia, weight loss, etc. Ultrasound in November 10 found 3.6*2.8 echogenic mass, in September 11 examined the right lobe of the liver on CT, found 4.6×3.4cm enhancement foci, blurred boundary, delayed period to see the envelope enhancement, the perihepatic, abdominal and lower thoracic cavity dorsum to see the fluid density, esophageal Intramural-like enhancement of the lower esophagus; slight thickening of the hepatic artery, originating from the celiac trunk, with three branches supplying the right liver, one of which is markedly thickened and supplies blood to the lesion; variant of the left hepatic artery, with questionable origin from the celiac trunk, evidence of portal hypertension, and splenic portal varicose vein. None,is seeking the best cure 1.would like to know the severity of the condition; 2.can the condition be operated on, the difficulty and danger of the operation; 3.will chemotherapy be required after the operation? Seeking the best program! Doctor: Hello: I don’t know whether you have a history of hepatitis B, and what is the condition of alpha-fetoprotein and liver function now! If the diagnosis of primary liver cancer is clear, the more recognized radical treatment means are liver cancer resection, radiofrequency ablation treatment for liver cancer, and liver transplantation! If the liver function is still good, surgical resection of liver cancer can be considered first, if the liver function is not so good, radiofrequency ablation of liver cancer can be considered, which is a kind of minimally invasive treatment, with little impact on the organism and quick recovery after the operation. In addition, liver transplantation is a good treatment for primary liver cancer patients who meet the Milanese criteria, but it is often limited by the shortage of donors, and in addition to the high cost, the patient is cannot be treated with liver transplantation in the short term or cannot afford the cost of liver transplantation! Therefore, the current treatment options for the eradication of your case are multiple and need to be chosen in the context of your specific situation!