Menopause is a stage that every woman must go through, and with the increase in the average life expectancy of women worldwide, women spend about 1/3 of their lives after menopause. The problems associated with menopause are diverse and seriously affect their quality of life, productivity and physical health. Evidence-based medicine shows that hormone supplementation therapy (HRT) is the only option that can comprehensively address these problems. The following data causes us gynecologists to think heavily: In foreign countries, the application rate of hormone supplementation therapy by gynecologic endocrinologists and their families is 100%, and the application rate of general women is 30-40%, however, in China, the application rate of general women is 1-2%. What a disparity! We can live a better life, why not make our life more exciting? I. Is hormone therapy necessary? Hormones are necessary for women, and it can be said that hormones accompany women throughout their lives. However, after entering menopause, with the failure of ovarian function and the decrease of estrogen, women will experience a series of problems: hot flashes, night sweats, sleep disorders, irritability, depression, anxiety, cardiovascular diseases, osteoporosis, memory loss, skin aging, urinary tract infections, vaginal dryness, sexual dysfunction and so on. The application of hormone supplementation therapy can well improve these symptoms, reduce the mortality rate of women and improve the quality of life, so hormone supplementation therapy is necessary! Second, is hormone therapy dangerous? When it comes to hormones, people will associate with images of glucocorticoids such as full-moon faces and buffalo backs, and feel that hormones are too scary, and fear of fat and cancer discourage people from hormones …… In fact, hormone supplementation therapy for menopausal women will not increase weight, but will instead improve women’s fat distribution, so that women will not become In fact, hormone supplementation therapy for menopausal women will not increase weight, but will improve the distribution of fat so that women will not become “apple-shaped” or have “swimming rings” around their waist after middle age. Also, can hormone supplementation therapy cause cancer? According to research, hormone replacement therapy (estrogen and progestin) treatment does not increase the risk of endometrial cancer, and the effect on the breast is minimal and the risk is rare, even lower than the risk of drinking two glasses of wine a day with obesity, so there is no claim that hormones cause cancer. The most common causes of death in women are coronary heart disease, stroke and fracture, etc. Hormone replacement therapy has a protective effect on cardiovascular, improves blood lipids and reduces bone loss, so it can be said that the advantages of hormone replacement therapy far outweigh the disadvantages. Third, how to make the benefits of hormone therapy outweigh the disadvantages? First of all, we should use the medication under the guidance of professional doctors, not at random. Doctors will individualize the medication according to each person’s situation. Secondly, we should grasp the “time window” of treatment. There is a concept of “time window” for hormone therapy, and it is safer to use medication within this time period. We advocate the use of drugs in the perimenopause and early menopause to maximize the benefits. Once again, strict follow-up is needed. Menopausal women should strictly follow their doctor’s instructions and make regular follow-up visits so that the doctor can adjust the plan for you at any time and assess whether you can continue to use it. Fourth, can hormone replacement therapy be used for uterine fibroids and other conditions? This requires a doctor’s assessment. Uterine fibroids within 3-4 cm in size can be treated with hormone replacement therapy under strict follow-up. This is because the amount of hormone produced by hormone replacement therapy is much less than the amount of hormone produced by the body before menopause. Hormone replacement therapy has strict indications, contraindications, and cautions, and requires a thorough evaluation. For example, endometriosis and early stage endometrial cancer can be treated with hormone replacement therapy under the strict follow-up of doctors after excluding contraindications. V. Can maintenance products and laser cosmetic treatments replace hormones? The answer is no. In today’s society, people’s awareness of health care has increased, and a large number of health care products have emerged: soy isoflavone products, collagen, etc. Do these things really work? Do these things really work and how much effect do they have? It is really hard to say. Some surveys have shown that due to hormone deficiency, 30% of collagen is lost in the first 5 years after menopause, so we will look old and wrinkles will creep up on our otherwise clean cheeks. That is why hormones are the most fundamental treatment. And soy isoflavones, an estrogen, are very weakly active, only 1 in 1,000 to 1 in 100,000 of estrogen. Why spend an expensive price on something whose effects are uncertain?