Acne is a chronic inflammatory skin disease of the sebaceous units of the hair follicles. It mainly occurs in adolescents and has a great psychological and social impact on them, but it can often be naturally reduced or cured after puberty. Clinical manifestations are characterized by polymorphic lesions such as acne, papules, pustules, and nodules, which are commonly found on the face. The occurrence of acne is closely related to excessive sebum secretion, blockage of sebaceous ducts, bacterial infection, and inflammatory reactions. After puberty, the level of androgens in the body, especially testosterone, rises rapidly, promoting the development of sebaceous glands and producing large amounts of sebum. At the same time, abnormal keratinization of the hair follicle sebaceous gland ducts causes duct blockage, resulting in obstruction of sebum drainage and formation of keratin plugs or microcomedones. A variety of microorganisms, especially Propionibacterium acnes, proliferate in the hair follicles. The lipase produced by Propionibacterium acnes breaks down sebum to produce free fatty acids and chemotactic inflammatory cells and mediators, eventually inducing and aggravating inflammatory reactions. Treatment 1, general treatment (1) Attention should be paid to washing the face with water, prohibiting hand squeezing and scratching acne, and in principle, no ointment cosmetics should be used. (2) Avoid spicy foods, control fat and sugar, and eat more fresh vegetables, fruits and vitamin-rich foods. (3) Combine work and rest, and correct constipation. 2, the lighter the ban on topical drugs can be. Reasonable choice of appropriate topical drugs, prohibit the use of hormonal ointment, which has no therapeutic effect will also lead to many side effects such as hormone-dependent dermatitis. 3, if necessary, can be combined with phototherapy, to help control inflammation, reduce scarring and acne marks.