In some patients, the lymph nodes on the ulcer side are enlarged due to the high inflammation of the mouth ulcer, and the symptoms of the lymph nodes necessitate the addition of antibiotics to eliminate the inflammation. Antibiotics can choose to use broad-spectrum antibiotics, such as erythromycin enteric capsules, azithromycin, etc., can also choose cephalosporins such as cefprozil, cefdinir, cefixime, etc., can also choose penicillin, such as amoxicillin, etc., patients can choose the appropriate antibiotics according to their own allergy situation. In addition, the patient should pay attention to the diet, do not eat spicy, irritating food and hairy products, while taking oral antibiotics can also use local medication for the ulcer site, you can choose to use open throat sword spray, stomatitis spray or watermelon cream spray on the affected area, can promote the healing of the ulcer, can also reduce the symptoms of swollen lymph nodes.