FAQ No. 4: Is fine needle aspiration useful for thyroid nodules? Will it lead to tumor metastasis? Lu Yingli, Department of Endocrinology, Ninth People’s Hospital, Shanghai Jiaotong University School of Medicine, many people casually understand and think that is fine needle puncture useful for thyroid nodules? Will it lead to tumor metastasis? At present, needle aspiration of thyroid nodules is the gold standard for determining the nature of thyroid nodules before surgery. The so-called “gold standard” means that it is the most accurate and reliable diagnostic method, and some literature reports that the accuracy of fine needle aspiration can reach more than 94%. As for whether it will cause tumor metastasis, there is no report of tumor implantation and metastasis due to fine needle aspiration. Therefore, it is nonsense that puncture can cause tumor metastasis.