Causes of nephritis are usually seen in infections, but can also be caused by drug toxicity that can cause drug nephritis. It can also be caused by other factors such as changes in the immune system, which can also cause nephritis, such as purpura nephritis and lupus nephritis. Nephropathy is usually caused by metabolic diseases, due to poor control of metabolic diseases such as hypertension, diabetes, gout and other metabolic diseases that cause damage to the kidneys is called nephropathy. Therefore, the causes of nephritis and nephropathy are different. Nephritis is mainly an alteration of the immune system, while nephropathy is an alteration of the metabolic system.