Hepatitis B virus-associated nephritis is associated with the hepatitis B virus, and China is a region with a high prevalence of hepatitis B. 16% of these patients develop extrahepatic manifestations, while 3% develop hepatitis B virus-associated nephritis. The specific principles of its treatment are specifically as follows: 1) reduce proteinuria; 2) prevent recurrence and try to prevent the occurrence of severe massive proteinuria; 3) protect and delay the progression of renal function. The specific treatment is related to the pathogenesis, because hepatitis B virus exists with E antigen and surface antigen, so the main pathological manifestations are membranous nephropathy and thylakoid proliferative nephropathy, so when developing glomerulonephritis, it is recommended to seek medical attention as early as possible, because some patients can be well cured.