In life, people encounter mental stress, life frustration, painful situation or birth, old age, sickness and death, etc., resulting in mood changes and feeling bad mood, but it does not mean that they suffer from depression. Normal people may experience mood swings during seasonal changes; in a month, especially for women, moods may change with the change of menstrual cycle; in a day, moods may be different in the morning and afternoon due to the fluctuation of hormone levels in the body; also, menopausal men and women often show unstable moods, which may be normal physiological phenomena leading to mood changes and need not be too nervous. Usually, these mood changes last for a short period of time and recover quickly after the environment or physiological conditions are normal. However, once the depression lasts longer than 2 weeks and seriously affects work, study and life, depression should be highly suspected, especially if it is accompanied by common symptoms of depression such as decreased interest, slowed thinking and reduced behavioral activities, you should consult a doctor as soon as possible for timely diagnosis and treatment. Special note: Typical depression has a rhythmical change of morning heavy and night light. In the early morning of each day, the patient’s mood is particularly low and painful, and even at this time the thought and behavior of dying for relief; after 3-4 pm, the patient’s mood gradually improves; in the evening, it seems that there is no more problem; however, the next morning, the patient is again in a morbid and difficult predicament.