1. Gout is a type of disease in which the abnormal metabolism of purine, a chemical in the body, causes an increase in blood uric acid, with arthritis, gout stones and kidney lesions as the main manifestations. 2, gout is most common in men aged 40 to 50 years, the incidence continues to rise, more and more young, 20-year-old young boys are also a lot, but women almost never have gout before menopause. 3, China before 1958 is very little, with the improvement of people’s living standards, the incidence only began to surge, indicating that the diet is very related, often accompanied by obesity, hyperlipidemia, diabetes and hypertension. The incidence of gout is very low until 1958, when it began to increase, indicating that it is related to diet and is often accompanied by obesity, hyperlipidemia, diabetes and hypertension, and is one of the core “diseases of affluence”. 4. The asymptomatic period lasts for several years to ten years, and at this time there is mostly hyperuricemia. 5, high purine food, alcohol consumption, cold or exertion and other factors are likely to trigger an acute attack of gout, with more attacks at night, the first attack on the first metatarsophalangeal joint of the foot is most common (50% to 90%), followed by the back of the foot, heel, ankle; about 5 years for knee attacks; about 10 years for wrist and metacarpophalangeal joints; the first attack does not start only from the upper limbs. The first attack does not start from the upper extremity only.6 The onset of the joint is characterized by localized redness, elevated skin temperature, swelling, and severe pain, often accompanied by general discomfort and fever. The first attack does not begin only in the limbs. 7. The former is caused by the deposition of calcium pyrophosphate crystals in the joints, slightly more in women than in men, with a predilection for age 60 years or older, mostly in the knee joint, and blood uric acid at normal levels. 10. The total calories should be limited to prevent overweight, and the diet should be based on rice and carbohydrates, supplemented by moderate amount of protein and low fat.11. Avoid high purine foods such as animal offal, seafood, yeast and beer. However, drinking wine in moderation is not harmful or even beneficial to gout.12. Drink more than 2000 ml of water, water, mineral water, soft drinks and fruit juices are good, strong tea, coffee and carbonated drinks are not recommended.13. You cannot eat only sparse vegetables and fruits, but are more prone to gout attacks, and should be properly supplemented with milk, eggs, refined meat and other proteins, and soy products are not absolutely forbidden, otherwise, because of hunger and increased lactic acid The gout is more likely to attack. The first choice for gout attack is no longer colchicine, but non-steroidal anti-inflammatory drugs and glucocorticoids in that order, and the dosage of colchicine has been significantly reduced to 0.5-1mg daily. 15. Antibiotics such as penicillin and vincristine are prohibited for gout attack, and uric acid-lowering drugs such as benzbromarone cannot be used. The medication used during the prevention period is very different.16. About 10% of hyperuricemia develops into gout, so hyperuricemia is not the same as gout. Gout attack is related to hyperuricemia, and the sudden high and low blood uric acid level is more likely to cause gout attack.17. The danger of asymptomatic hyperuricemia is to increase blood vessel wall damage, which has become an independent risk factor for coronary heart disease, myocardial infarction and brain infarction.18. About 90% of hyperuricemia is mainly caused by kidney excretion dysfunction, and a high purine diet just adds to the gout attack period. Sometimes check uric acid instead of high. 19, gout, obesity, hyperlipidemia, hypertension, diabetes, etc., should be treated at the same time, otherwise poor, gout early attack is not a difficult problem, the key is the kidney, vascular damage and late extensive joint deformation is more terrible. 20, new advances and biological agents, such as uricase can quickly dissolve gout stones, but easy allergy, effectiveness is not long.