High estradiol is not premature ovarian failure. The main manifestation is early amenorrhea, often accompanied by hot flashes, night sweats and insomnia and other menopausal symptoms, hormonal manifestations of estradiol decline, luteinizing hormone and follicle stimulating hormone significantly higher, which is often said to be two high and one low, such as ovarian surgery, long-term anxiety or stay up late on women’s ovaries are very unfavorable. The reason is that premature ovarian failure can lead to some problems such as osteoporosis and cardiovascular problems, so women should try to avoid these unfavorable factors, after all, ovarian function is very important for women, if the ovaries fail prematurely means that women may age early. The main reason for the premature ovarian failure in Chinese medicine is the deficiency of kidney yin, so the treatment will use some kidney nourishing Yin Chinese medicine to regulate, but also with acupuncture or ear acupuncture treatment, these can play a certain effect. In conclusion, premature ovarian failure is mainly due to a decline in estradiol, not an increase in estradiol. The woman should maintain a good state of mind, eat more soy products, supplement estrogen through dietary therapy, do not stay up late for a long time, do a good job of contraception, try to avoid abortion and other procedures, these are beneficial for the maintenance of the ovaries.