The turnaround time for HPV infection in men is related to their type and cannot be generalized. Some high-risk types take a shorter time to turn negative, about 6-8 months, and in severe cases it may take up to two years to turn completely negative. There are two main types of HPV infection in men, high-risk and low-risk. Low-risk types, including HPV types 6 and 11, can cause genital warts, such as condyloma acuminatum, and are easily transmitted through sexual intercourse. High-risk types, namely HPV type 16 and HPV type 18, are mainly associated with anal cancer and oral cancer. There is no effective drug treatment for HPV virus, which can be self-healing through its own immune ability. For simple HPV infection, regular review is sufficient and no drug intervention is needed; if there are lesions in the external genital area, pathological examination is needed to clarify the diagnosis and take appropriate treatment. In addition, patients should keep as few sexual partners as possible and use condoms during intercourse to avoid HPV infection to a certain extent, and should abstain from smoking and alcohol.