1.What are the matters of attention in growth hormone therapy? The correct dose of rhGH should be injected under the guidance of a doctor; injected half an hour before bedtime every night; it is best for parents to learn to inject themselves to avoid wasting; the injection site should be changed; and proper exercise should be adhered to during treatment to facilitate full absorption of the drug. It is only scientific to judge under the same ruler and conditions. It is best not to adjust the amount and stop the medication by yourself. 2.What are the side effects of growth hormone treatment? (1) Local transient reactions (pain, tingling, redness, swelling, etc.) and symptoms of fluid retention (peripheral edema, arthralgia or myalgia) at the injection site, the incidence of which has been reduced; (2) Antibody production, which may affect the efficacy, but the incidence of aqueous doses is low; (3) Hypothyronemia; temporary hypoglycemia; (4) Femoral head necrosis, slippage; (5) Idiopathic intracranial pressure elevation: headache, vomiting, etc. (6) possibility of tumor induction: there is no clear evidence yet. (3) Caution should be exercised for people with family history of tumor and long-term supraphysiological doses of growth hormone. The growth hormone currently used is genetically recombinant, and its molecular structure is exactly the same as that of human growth hormone, and since it is a replacement therapy, side effects are relatively rare. However, during the course of growth hormone treatment, it is still necessary to follow up with the doctor’s advice at regular intervals at a hospital specialist clinic. Regular height measurements, IGF-1, T4, TSH, blood glucose and insulin tests should be performed in order to adjust the GH dose and thyroid hormone supplementation in a timely manner. Bone age should be checked once every six months. Sexual development should be observed during the course of treatment and treated as needed. Those with suspected intracranial lesions should be noted for regular repeat cranial MRI, etc.