What Patients Need to Know During Growth Hormone Therapy

  I. What are the things to note in growth hormone therapy?  The correct dose of rhGH should be injected under the guidance of the doctor; it should be injected half an hour before bedtime every night; it is best for parents to learn how to inject themselves to avoid wastage; the injection site should be changed; and exercise should be insisted on during the treatment period to facilitate the full absorption of the drug. It is only scientific to judge under the same ruler and conditions. It is best not to adjust the dosage and stop the medication by yourself.  What are the side effects of growth hormone treatment?  Local transient reactions (pain, tingling, redness, swelling, etc.) and symptoms of fluid retention (peripheral edema, arthralgia or myalgia) at the injection site, the incidence of which is now less; antibody production, which may affect the efficacy, but the incidence of aqueous doses is low; hypothyronemia; temporary hypoglycemia; femoral head necrosis, slippage; idiopathic increase in intracranial pressure: headache, vomiting, etc.; possibility of inducing tumors: there is no There is no definite evidence.  Caution is needed for those with a family history of tumors and those with long-term supraphysiological doses of growth hormone.  The growth hormone currently used is genetically recombinant, and its molecular structure is exactly the same as that of human growth hormone, and since it is a replacement therapy, the occurrence of side effects is relatively rare. However, during the course of growth hormone treatment, it is still necessary to follow up with the doctor’s advice at regular intervals at a hospital specialist clinic. Regular height measurements, IGF-1, T4, TSH, blood glucose and insulin tests should be performed in order to adjust the GH dose and thyroid hormone supplementation in a timely manner. Bone age should be checked once every six months. Sexual development should be observed during the course of treatment and treated as needed. Those suspected of intracranial lesions should be noted for regular repeat cranial MRI, etc.  If you have any questions about your child’s growth, you can leave a message online and I will reply to you at my convenience.