Hepatobiliary Surgery Department has introduced a new type of targeted tumor radiofrequency ablation therapy instrument produced in the United States, which can be operated by laparoscopy, surgery or percutaneous puncture under the guidance of CT or ultrasound, etc. Meanwhile, needle tract ablation can prevent needle tumor implantation. It has treated a large number of patients with mid- to late-stage tumors in hepatobiliary surgery with remarkable efficacy. The treatment effect is better with the combination of DSA tumor embolization chemotherapy and 125I particle inter-tissue implantation technology. RFA technology is an emerging minimally invasive treatment technology for benign and malignant tumors in recent years. Its principle is to transmit high-powered radiofrequency energy to the tumor through the ablation electrode, so that the positive and negative ions in the tumor change rapidly with the direction of the radiofrequency alternating current, causing the tumor tissue itself to generate frictional heat, and when the temperature reaches 60oC or above, the tumor tissue undergoes irreversible coagulative necrosis. This technique is safe, effective, precise and easy to operate, and it takes about 30 minutes to complete radiofrequency ablation of 5cm tumor. Indications: inoperable primary liver cancer, liver metastasis, pancreatic cancer, gallbladder cancer, bile duct cancer and spleen tumor. 125I particle inter-tissue implantation for malignant tumors This technique has been successfully introduced in our hepatobiliary surgery department to treat some patients with intermediate to advanced pancreatic cancer and liver cancer, with obvious efficacy. It is also combined with our DSA tumor embolization chemotherapy and radiofrequency ablation technology to achieve better treatment effect. What is tumor particle implantation: Tumor particle implantation is a new treatment technology that uses tumor image materials obtained from CT and B-ultrasound combined with computer simulation planning system for precise design and conventional surgery or minimally invasive techniques to implant tiny radioactive particles evenly into tumor tissues as needed and use the close range radiation emitted by the particles to kill the tumor directly. It is another new and ideal technological progress in the process of tumor treatment. Advantages of particle implantation therapy: 1. The radiation does not pass through the normal organs, and the area of action is strictly limited to the clinically required range, which has less impact on normal tissues and relatively low radiation-related long term complications. 2. 4.After implantation, it is safe and reliable. The particle radiation is low-energy close range radiation, the action distance is only 2cm, the shielding is simple, and it has no effect on the surrounding people. Indications for particle implantation: 1. primary tumors (such as pancreatic cancer, liver cancer, gallbladder cancer, bile duct cancer, spleen tumors, gastrointestinal tumors, etc.); 2. remaining cancerous tissues removed by local surgery; 3. important tissues accumulated by the spread of primary foci; 4. more isolated metastatic cancer; 5. palliative treatment of middle and late stage tumors.