The life expectancy of patients with autoimmune liver disease is chronic and depends on the early detection of the disease, timely treatment, the effectiveness of treatment, and the degree of attention paid by the patient. If early detection, timely treatment and certain attention are given, patients usually have a relatively good prognosis, and it usually takes 10-20 years or more from the appearance of clinical symptoms to advanced cirrhosis. If hormones, immunosuppressants and biological agents are actively used, the survival time of patients can be extended as long as possible. If patients are found late, not treated in time, and do not pay attention to themselves, the survival period is 50% in three years and only 10% in five years. Patients should not lose their confidence in treatment, and it is recommended to choose a regular hospital for liver disease consultation without delay. Active treatment, proper exercise, and dietary modification can maximize disease control and prolong survival time.