40-year-old Ms. Wu, recently in eating fruit or brushing teeth often gum bleeding, and even suck a little harder, spit out the saliva will also have red. Ms. Wu thought her gums out of the problem, to the dental hospital to see the doctor, the doctor said there is no obvious inflammation of the gums, let her go to the local hospital internal medicine to see, check the blood routine, this check, put Ms. Wu stunned, the blood routine shows a decrease in white blood cells to more than 2000, platelets only 70,000/μL (70 × 10^9 / L), two indicators are significantly lower than normal, clotting time measurement, bleeding time prolonged . Ms. Wu wondered if she had a blood-related disease. Thinking back to the usual inexplicable appearance of cyanotic spots on her body, she became more nervous and went to the hematology department, which did relevant tests and also did a bone marrow aspiration, ruling out hematological diseases, checking abnormal liver function, and suggesting that she look at the gastroenterology department. Zhang Zhaolan, Department of Spleen, Gastrointestinal, Liver and Gallbladder Diseases, The First Affiliated Hospital of Henan College of Traditional Chinese Medicine Ms. Wu came to the Department of Spleen, Gastrointestinal, Liver and Gallbladder Diseases, The First Affiliated Hospital of Henan College of Traditional Chinese Medicine on the recommendation of a patient and found me to see her. After carefully inquiring about Ms. Wu’s medical history, medication and family situation, and having Ms. Wu undergo liver function, liver ultrasound and virological and autoimmune hepatitis tests for hepatitis B and C, I told Ms. Wu that you have post-hepatitis B viral cirrhosis. Because cirrhosis is a common chronic progressive liver disease with insidious onset and no obvious clinical symptoms at the beginning. In China, most of them are cirrhosis caused by hepatitis B and C, and a few are alcoholic cirrhosis and schistosomiasis cirrhosis. Pathological histology has extensive hepatocyte necrosis, nodular regeneration, connective tissue hyperplasia and fibrous septum formation, leading to structural destruction of liver lobules and pseudobullet formation, and progressive deformation and hardening of the liver to cirrhosis. Ms. Wu’s bleeding gums and petechiae on her body are the result of hypersplenism. Because cirrhosis tends to cause elevated portal pressure, the spleen becomes congested and enlarged, causing blood to pool in the liver, resulting in increased mechanical damage to the blood, leading to a decrease in white blood cells and platelets. The main function of platelets is to clot and stop bleeding, and repair broken blood vessels. A blood platelet count of less than 100,000/μ1 (100 x 10^9/L) is considered thrombocytopenia, and less than 50,000/μL (50 x 10^9/L) is a risk for bleeding. Because the hepatitis B / C hepatitis virus infection process is more insidious, coupled with strong liver compensatory function, early cirrhosis can be no obvious symptoms, some like Ms. Wu bleeding gums, nasal bleeding or subcutaneous petechiae before visiting the hospital, some are physical examination only to find that has been the cirrhosis of the liver. If left untreated, liver function damage and symptoms of portal hypertension will appear in the late stage of cirrhosis, and several systems will be damaged. Complications such as upper gastrointestinal bleeding, hepatic encephalopathy, secondary infection, hypersplenism, ascites and liver cancer often occur in the late stage. Ms. Wu’s main concern is how to treat it? How to control the disease from progressing to the bad side? In Ms. Wu’s case, although she has reached cirrhosis, her liver function is currently in the compensatory phase. The first step is antiviral treatment, the goal of which is to maximize long-term suppression of HBV, reduce liver inflammation necrosis and liver fibrosis, delay and reduce the occurrence of cirrhosis, decompensation and liver cancer, thus improving the patient’s quality of life and extending survival time. In Chinese medicine, cirrhosis is classified as an “accumulation” disease, which belongs to the “accumulation” disease in Chinese medicine. The cause of cirrhosis is that the evil of epidemic toxin (hepatitis B virus) stays in the liver, resulting in damage to the liver and spleen, loss of harmony between the organs, stagnation of qi, and internal stagnation of blood. If left untreated, the disease spreads and damages the kidneys, resulting in damage to the liver, spleen and kidneys, stagnation of qi and blood, water stagnation in the abdomen, and ascites. According to Ms. Wu’s condition, we formulated a treatment plan for her: taking nucleoside antiviral drugs orally to control the replication of hepatitis B virus and eliminate the source of the disease, and using Chai Hu Shu Huan San plus reduction to dredge the liver and regulate Qi, invigorate blood and eliminate accumulation. Combine with blood cooling and heat clearing drugs. After 3 months of treatment, Ms. Wu’s condition was effectively controlled, and her laboratory tests showed that her HBV-DNA turned negative, her liver function was normal, and her gum bleeding symptoms disappeared. Nearly 1 year follow-up, Ms. Wu has become optimistic and cheerful, and all the examination indexes have been normal. Therefore, in daily life, if our body appears abnormal state, do not take it for granted that you are suffering from any disease, you should go to the hospital to avoid delaying the disease.